Pigmented Spindle Cell Nevus of Reed Dermatopathology
Pigmented spindle cell nevus is a benign melanocytic lesion that was initially described in 1975 by Reed et al. It is generally found on the trunk or lower extremities of young women. Most authors consider it to be a variant of Spitz nevus. The main concern with these lesions remains their propensity to mimic melanoma both clinically and histologically.
Figure 1 from Pigmented Spindle Cell Nevus of Reed of the Eyelid Semantic Scholar
Clinically, pigmented Spitz/Reed nevi are brown to black, flat to slightly elevated, symmetrical lesions showing a relative preference for certain locations, including face, limbs and buttocks. The most relevant and peculiar feature is the starburst pattern seen by dermoscopy. This is typified by multiple streaks of pigmentation or large.
Dermpath Made Simple Neoplastic Spitz Nevus and Reed Nevus
Differential diagnosis of Spitz and Reed naevi. The differential diagnosis of Spitz and Reed naevi includes acquired melanocytic naevi, blue naevi and melanoma.. Spitz tumours with kinase fusions. It has recently been shown that spitzoid neoplasms harbour kinase fusions of ROS1 (17%), NTRK1 (16%), ALK (10%), BRAF (5%) and RET (3%) in a mutually exclusive pattern.
Pigmented Spindle Cell Nevus of Reed Dermatopathology
Update on dermoscopy of Spitz/Reed naevi and management guidelines by the International Dermoscopy Society Br J Dermatol. 2017 Sep;177(3):645-655. doi: 10.1111/bjd.15339.. Nevus, Epithelioid and Spindle Cell / pathology Nevus, Epithelioid and Spindle Cell / therapy*.
Reed nevus on the finger (A) Clinical features of the lesion. (B)... Download Scientific Diagram
Pigmented spindle cell nevus (PSCN) of Reed is a morphologic variant of Spitz and may be very diagnostically challenging, having histologic features concerning for melanoma. Their occurrence in younger patients, lack of association to sun exposure, and rapid early growth phase similar to Spitz nevi suggest fusions may also play a significant.
Clinical features and natural history of SpitzReed nevus in children. Semantic Scholar
Reed nevus is composed histologically of elongated spindle-shaped and nevoid cells with a benign biologic behavior. Histopathological features in common with Spitz nevi and in contrast with malignant melanoma include a relatively small size, lesion symmetry, uniformity of cell type, good circumscription, and maturation of cells from superficial.
Starburst dermoscopic pattern of Reed nevus Download Scientific Diagram
The Reed Nevus or pigmented spindle cell nevus (PSCN) was first described by Reed et al. in 1975 . Its designation as a separate entity vs. a SN variant remains controversial, but is currently considered by the 2018 WHO Classification to be a "distinct variant of Spitz naevus.".
Dermoscopy Made Simple Reed Nevus
The Spitz naevus (syn. spindle cell naevus, epithelioid cell naevus, juvenile melanoma) is a variant of a compound naevus and is most commonly seen in children . The pigmented spindle cell naevus of Reed (PSCNOR) is a variant of a compound or occasionally a junctional naevus. There is debate as to whether the PSCNOR is an entity in its own.
Nevus definition, types, diagnosis & nevus treatment
The clinical-dermatoscopic-histological correlation of excised Spitz/Reed nevi revealed overlapping histopathological features among lesions displaying distinct dermatoscopic patterns ( Figures 1 - 3 ). Among lesions with histopathological atypia (16/47, 34.0%), all dermatoscopic patterns were represented, although the atypical/multicomponent.
Dermoscopy of Pigmented Spitz and Reed Nevi The Starburst Pattern Dermatology JAMA
Spitz naevus is classified as classic, pigmented, or spindle cell tumour of Reed. The classic Spitz naevus is typically a dome-shaped red, reddish-brown papule. A pigmented Spitz naevus is a tan or brown papule or nodule. A pigmented spindle cell tumour of Reed is a bluish or black papule. There are clinical features in common for all three.
Evolution of Reed Nevi Dermoscopic Pattern in Childhood Dermatology JAMA Dermatology JAMA
Reed nevus (also known as pigmented spindle cell nevus of Reed) is an acquired, benign, melanocytic lesion most frequently classified as a variant of a Spitz nevus. A Reed nevus typically presents as an asymptomatic, single, 2-8 mm, dark brown to black macule or papule on the lower extremities of young adults. The lesion may also be found in.
Dermatoscopic patterns of Reed nevus. Starburst pattern in which black,... Download Scientific
Symmetric with cytologic maturation. Nests and fascicles of spindled melanocytes along dermoepidermal junction and within dermal papillae. May be junctional or compound. Expansive, not infiltrative growth pattern. Extends no deeper than reticular dermis. Nevus cells typically contain abundant melanin pigment, may be associated with melanophages.
Pigmented Spindle Cell Nevus of Reed Dermatopathology
The histopathologic distinction between Spitz nevus and Reed nevus is often matter of great debate. Nowadays, we distinguish two clinical variants of SN, the classical and the pigmented types, the latter include Reed nevus. The most important issue of SN is their propensity to mimic melanoma clinically, dermatoscopically and histopathologicallly.
Naevus van Reed (pigmented spindle cell nevus)
'Nevus, Reed' published in 'Dermatopathology' Pigmented spindle cell nevus is a sharply demarcated and symmetrical melanocytic lesion characterized by a florid and cellular junctional component and marked melanin pigmentation (Fig. 1).The junctional aspect is composed of large and prominent nests containing uniform, spindled melanocytes arranged in fascicles with a characteristic vertical.
Nevo de Reed. Diagnóstico dermatoscópico de un caso PIELL Latinoamericana
A Reed naevus is a very dark pigmented melanocytic naevus with spindle-shaped dermal melanocytes on histology. It was first reported by dermatologist Richard Reed in 1975. It is also known as a spindle cell naevus. Reed naevus is sometimes classified as a kind of Spitz naevus; the spindle-shaped cells of the Reed naevus may coexist with the.
Dermpath Made Simple Neoplastic Spitz Nevus and Reed Nevus
Reed nevus is considered a pigmented variant of Spitz nevus. It usually appears during childhood, adolescence or early adulthood, and commonly appears on the lower limbs of female patients. After 6 months of rapid growth, Reed nevus tends to show no more enlargements over time. The starburst pattern is the dermatoscopic hallmark of Reed nevus.
